Who was studied?
90 male BALB/c mice in a CT26.WT tumor-model experiment.
What does the publication report?
The reported changes included a lower CD4+ T-cell proportion, higher CD8+ T-cell proportion and fewer granulocytic suppressor cells.
Safety findings
Animal research does not establish human safety.
How should we interpret it?
An early meeting report related to the later peritoneal-model publication. The experiments and populations are not assumed to be independent.
Read the original source
This independently written summary was checked against the publicly available abstract. Selected figures, where included, are checked against the full publication. This is not a full-paper translation or a clinical recommendation.
Impact of PRaG Therapy on Peripheral Immune Cells of Subcutaneous Tumor Peritoneal Metastasis Model of Colon Cancer · DOI: 10.1016/j.ijrobp.2023.06.1201
Related publications from the same research program
- The Anti-tumor Effect and Immunological Cell Changes of PRaG Therapy in Colon Cancer Peritoneal Metastasis of Mice
- Study of effect of PRaG therapy in colon cancer transplanted tumor mouse model
Educational reporting, not individualized medical advice. Discuss treatment decisions with your clinical team.